Coupled plasma filtration adsorption in peritonitis-induced porcine hyperdynamic septic shock
نویسندگان
چکیده
منابع مشابه
A pilot study of coupled plasma filtration with adsorption in septic shock.
OBJECTIVE To test the hypothesis that nonselective plasma adsorption by a hydrophobic resin (coupled plasmafiltration and adsorption) could improve hemodynamics and restore leukocyte responsiveness in patients with septic shock. DESIGN Prospective, pilot, crossover clinical trial. SETTING General intensive care unit in a teaching hospital. SUBJECTS Ten patients with hyperdynamic septic sh...
متن کاملEfficacy of coupled plasma filtration adsorption (CPFA) in patients with septic shock: A multicenter randomised controlled clinical trial
OBJECTIVES Coupled plasma filtration adsorption (CPFA, Bellco, Italy), to remove inflammatory mediators from blood, has been proposed as a novel treatment for septic shock. This multicenter, randomised, non-blinded trial compared CPFA with standard care in the treatment of critically ill patients with septic shock. DESIGN Prospective, multicenter, randomised, open-label, two parallel group an...
متن کاملcoupled plasma filtration and adsorption (cpfa): a single center experience
conclusions the high prevalence of fungaemia and mortality could be attributed to many patients on chronic immunosuppressive therapy. nonetheless, cpfa albeit expensive, does add to our armamentarium of extracorporeal treatment for severe sepsis. regional citrate anticoagulation with cpfa may overcome problems with filter clotting. objectives the main objective was to review our centers' e...
متن کاملThe Use of Coupled Plasma Filtration Adsorption in Traumatic Rhabdomyolysis
Severe musculoskeletal injuries induce the release of sarcoplasmic elements such as muscle enzymes, potassium, and myoglobin in the systemic circulation. The circulating myoglobin damages the glomerulus and renal tubules. Conventional haemodialysis is not able to remove myoglobin, due to its high molecular weight (17,8 kilodaltons [kDa]). We treated four traumatic rhabdomyolysis patients with C...
متن کاملCoupled Plasma Filtration and Adsorption (CPFA): A Single Center Experience
BACKGROUND Coupled plasma filtration adsorption (CPFA) is a novel extracorporeal blood purification therapy for sepsis which adsorbs both proinflammatory and anti-inflammatory mediators from filtered plasma, thereby achieving early haemodynamic stability and a reduction in inotropic support requirement. OBJECTIVES The main objective was to review our centers' experience with CPFA in septic pa...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2008
ISSN: 1364-8535
DOI: 10.1186/cc6681